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Article

ALK-mutated non-small-cell lung cancer: a new strategy for cancer treatment.

Lung - 1 Aug 2012

Cabezón-Gutiérrez Luis, Khosravi-Shahi Parham, Diaz-Muñoz-de-la-Espada Victor Manuel, Carrión-Galindo Jose Rafael, Eraña-Tomás Itziar, Castro-Otero María

Abstract excerpt

The anaplastic lymphoma kinase (ALK) tyrosine kinase (TK) receptor has emerged recently as a potentially relevant biomarker and therapeutic target in solid and hematologic tumors. A variety of alterations in the ALK gene, such as mutations, overexpression, amplification, translocations, or other structural rearrangements, have been implicated in human cancer tumorigenesis. In this article we review the potential...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 22584871
DOI: 10.1007/s00408-012-9391-y

Genes

ALK

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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