Article
Integration of disease-specific single nucleotide polymorphisms, expression quantitative trait loci and coexpression networks reveal novel candidate genes for type 2 diabetes.
Diabetologia - 1 Aug 2012
Kang H P, Yang X, Chen R, Zhang B, Corona E, Schadt E E, Butte A J
Abstract excerpt
AIMS/HYPOTHESIS: While genome-wide association studies (GWASs) have been successful in identifying novel variants associated with various diseases, it has been much more difficult to determine the biological mechanisms underlying these associations. Expression quantitative trait loci (eQTL) provide another dimension to these data by associating single nucleotide polymorphisms (SNPs) with gene expression. We...
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