Article
Identification of Gene Signature Associated with Type 2 Diabetes Mellitus by Integrating Mutation and Expression Data.
Current gene therapy - 1 Jan 2022
Zhu Zijun, Han Xudong, Cheng Liang
Abstract excerpt
BACKGROUND: Type 2 Diabetes Mellitus (T2DM) is a chronic disease. The molecular diagnosis should be helpful for the treatment of T2DM patients. With the development of sequencing technology, a large number of differentially expressed genes were identified from expression data. However, the method of machine learning can only identify the local optimal solution as the signature. OBJECTIVE: The mutation information...
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