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Article

Treatment directed to signalling molecules in patients with advanced differentiated thyroid cancer.

Anti-cancer agents in medicinal chemistry - 1 Mar 2013

Sáez Jose M G

Abstract excerpt

Mutation detection in samples from thyroid cancer with the addition of BRAF mutation, and also the detection of RAS, RET/PTC, and PAX8/PPARγ mutations, may also contribute to cancer diagnosis. On the other hand, the MAPK/ERK (mitogen-activated protein kinase/extracellular signal-regulated kinase signaling pathway) and PI3K/Akt (lipid kinase phoshoinositid-3-kinase signaling pathway) play an important role in the...

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Share to Adenocarcinoma, Follicular
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Share to Extracellular Signal-Regulated MAP Kinases

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Phosphatidylinositol 3-Kinases

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Share to Thyroid Neoplasms

Source

Identifiers

PMID: 22583421
DOI: 10.2174/1871520611313030011

Genes

RET
BRAF
PAX8
PTEN

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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