Article
How molecular pathology is changing and will change the therapeutics of patients with follicular cell-derived thyroid cancer.
Journal of clinical pathology - 1 May 2009
Couto J Pinto, Prazeres H, Castro P, Lima J, Máximo V, Soares P, Sobrinho-Simões M
Abstract excerpt
Well-differentiated thyroid carcinomas comprise two well-defined histological types: papillary and follicular (PTCs and FTCs, respectively). Despite being derived from the same cell (thyroid follicular cell), these two types of tumour accumulate distinct genetic abnormalities during progression. The molecular pathology of thyroid cancer is now better understood because of our ability to identify RET/PTC...
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