Article
Development and characterization of murine monoclonal antibodies to first and second Ljungan virus genotypes.
Journal of virological methods - 1 Sept 2012
Kallies René, Arbrandt Gustav, Niklasson Bo, Niedrig Matthias
Abstract excerpt
Ljungan virus (LV) is a rodent pathogen that causes diabetes and myocarditis in its natural host. In addition, LV has been associated with human disease during pregnancy and of neonates, respectively. A panel of 22 monoclonal antibodies (mAbs) against first and second LV genotypes were produced by immunization of BALB/c mice with whole virus. Thirteen mAbs were class IgG antibodies and nine were class IgM...
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