Article
Inefficient cerebral recruitment as a vulnerability marker for schizophrenia.
Psychological medicine - 1 Jan 2013
Liddle E B, Bates A T, Das D, White T P, Groom M J, Jansen M, Jackson G M, Hollis C, Liddle P F
Abstract excerpt
BACKGROUND: Patients with schizophrenia and their first-degree relatives exhibit both abnormally diminished and increased neural activation during cognitive tasks. In particular, excessive task-related activity is often observed when tasks are easy, suggesting that inefficient cerebral recruitment may be a marker of vulnerability for schizophrenia. This hypothesis might best be tested using a very easy task, thus...
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