Article
Functional magnetic resonance imaging during auditory verbal working memory in nonpsychotic relatives of persons with schizophrenia: a pilot study.
Biological psychiatry - 1 Mar 2004
Thermenos Heidi W, Seidman Larry J, Breiter Hans, Goldstein Jill M, Goodman Julie M, Poldrack Russell, Faraone Stephen V, Tsuang Ming T
Abstract excerpt
BACKGROUND: First-degree relatives of persons with schizophrenia carry elevated genetic risk for the illness and show deficits on high-load information processing tasks. We used functional magnetic resonance imaging (fMRI) to test whether nonpsychotic relatives show altered functional activation in the prefrontal cortex (PFC), thalamus, hippocampus, and anterior cingulate during a working memory task requiring...
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