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Exaggerated brain activation during emotion processing in unaffected siblings of patients with schizophrenia.

Biological psychiatry - 1 Jul 2011

van Buuren Mariët, Vink Matthijs, Rapcencu Anca E, Kahn René S

Abstract excerpt

BACKGROUND: Schizophrenia is characterized by impaired social cognition, including emotion processing. Behavioral studies have reported impaired performance on various emotion processing tasks, and imaging studies in patients have observed aberrant activity within the underlying neural circuitry. Also, subjects at increased genetic risk of developing schizophrenia, including unaffected siblings of patients, show...

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PMID: 21531384
DOI: 10.1016/j.biopsych.2011.03.011

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