Article
Evidence that altered amygdala activity in schizophrenia is related to clinical state and not genetic risk.
The American journal of psychiatry - 1 Feb 2009
Rasetti Roberta, Mattay Venkata S, Wiedholz Lisa M, Kolachana Bhaskar S, Hariri Ahmad R, Callicott Joseph H, Meyer-Lindenberg Andreas, Weinberger Daniel R
Abstract excerpt
OBJECTIVE: Although amygdala dysfunction is reported in schizophrenia, it is unknown whether this deficit represents a heritable phenotype that is related to risk for schizophrenia or whether it is related to disease state. The purpose of the present study was to examine amygdala response to threatening faces among healthy siblings of schizophrenia patients in whom a subtler heritable deficit might be observed....
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