Article
A Three-Dimensional Cell Culture Platform for Long Time-Scale Observations of Bio-Nano Interactions.
ACS nano - 26 Nov 2019
Muraca Francesco, Alahmari Amirah, Giannone Valeria A, Adumeau Laurent, Yan Yan, McCafferty Mura M, Dawson Kenneth A
Abstract excerpt
We know surprisingly little about the long-term outcomes for nanomaterials interacting with organisms. To date, most of what we know is derived from in vivo studies that limit the range of materials studied and the scope of advanced molecular biology tools applied. Long-term in vitro nanoparticle studies are hampered by a lack of suitable models, as standard cell culture techniques present several drawbacks,...
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