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Hepatitis C Virus and Liver Disease: Global Transcriptional Profiling and Identification of Potential Markers

25 Nov 2003

Abstract excerpt

Microarray analysis of RNA from hepatitis C virus (HCV)-infected cirrhotic livers was performed to identify a gene expression signature of liver disease. The expression levels of approximately 13600 genes were analyzed using surgical material and core biopsy specimens from HCV-infected cirrhotic liver explants in comparison with reference samples of normal nondiseased liver. In addition, normal liver samples were...

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PMID: 14647057
DOI: 10.1016/j.hep.2003.09.024

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