Article
The new platelet alloantigen Cab a: a single point mutation Gln 716 His on the alpha 2 integrin.
Transfusion - 1 Oct 2009
Bertrand Gerald, Jallu Vincent, Saillant Dominique, Kervran Dominique, Martageix Corinne, Kaplan Cecile
Abstract excerpt
BACKGROUND: Fetal/neonatal alloimmune thrombocytopenia (FNAIT) is caused by maternal alloimmunization against fetal platelet (PLT) antigens, inherited from the father and absent from maternal PLTs. STUDY DESIGN AND METHODS: A 29-year-old mother gave birth to a severely thrombocytopenic newborn (16 x 10(9) PLTs/L) leading to PLT transfusion therapy associated with intravenous immunoglobulins. The outcome was...
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