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Article

A single polar residue and distinct membrane topologies impact the function of the infectious bronchitis coronavirus E protein.

PLoS pathogens - 1 Jan 2012

Ruch Travis R, Machamer Carolyn E

Abstract excerpt

The coronavirus E protein is a small membrane protein with a single predicted hydrophobic domain (HD), and has a poorly defined role in infection. The E protein is thought to promote virion assembly, which occurs in the Golgi region of infected cells. It has also been implicated in the release of infectious particles after budding. The E protein has ion channel activity in vitro, although a role for channel...

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Identifiers

PMID: 22570613
DOI: 10.1371/journal.ppat.1002674
PMCID: PMC3343006

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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