Article
CNR1 genotype influences HDL-cholesterol response to change in dietary fat intake.
PloS one - 1 Jan 2012
Silver Heidi J, Niswender Kevin D, Keil Charles D, Jiang Lan, Feng Qiping, Chiu Sally, Krauss Ronald M, Wilke Russell A
Abstract excerpt
BACKGROUND: Success in further reducing the burden of cardiovascular disease (CVD) is threatened by the increasing prevalence of obesity-related atherogenic dyslipidemia. HDL-cholesterol (HDL-C) level is inversely correlated with CVD risk; each 1 mg/dl decrease in HDL-C is associated with a 6% reduction in risk. We previously showed that a common CNR1 haplotype, H3 (frequency 20%), is protective against the...
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