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Article

HSP60: Issues and Insights on Its Therapeutic Use as an Immunoregulatory Agent

1 Jan 2012

Abstract excerpt

Heat shock proteins 60 (HSP60) is one of the most well studied member of the HSP family. Although found to be a target self antigen in pathological autoimmunity and HSP60-reactive T and B cells are part of immune responses in several infectious diseases, there is consistent experimental evidence that HSP60 displays dominant immunoregulatory properties. There are a series of reports on animal models showing that...

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PMID: 22566886
DOI: 10.3389/fimmu.2011.00097

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