Article
The -174G/C variant of IL6 as risk factor for mortality and technique failure in a large cohort of peritoneal dialysis patients.
Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association - 1 Sept 2012
Verduijn Marion, Maréchal Céline, Coester Annemieke M, Sampimon Denise E, Boeschoten Els W, Dekker Friedo W, Goffin Eric, Krediet Raymond T, Devuyst Olivier
Abstract excerpt
BACKGROUND: Functional variants in the IL6 gene, in particular the -174G/C polymorphism (rs1800795), affect the mortality risk in dialysis patients. Peritoneal dialysis (PD) patients harbouring the C allele of the -174G/C polymorphism of IL6 showed faster peritoneal transport. The aim of this stu...
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