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Article

Inferring high-confidence human protein-protein interactions.

BMC bioinformatics - 4 May 2012

Yu Xueping, Wallqvist Anders, Reifman Jaques

Abstract excerpt

BACKGROUND: As numerous experimental factors drive the acquisition, identification, and interpretation of protein-protein interactions (PPIs), aggregated assemblies of human PPI data invariably contain experiment-dependent noise. Ascertaining the reliability of PPIs collected from these diverse studies and scoring them to infer high-confidence networks is a non-trivial task. Moreover, a large number of PPIs share...

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Share to Databases, Protein
Share to Genetic Predisposition to Disease
Share to Multiprotein Complexes

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Polymorphism, Single Nucleotide

Share to Protein Interaction Mapping

Share to Protein Interaction Maps

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Share to Reproducibility of Results

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Identifiers

PMID: 22558947
DOI: 10.1186/1471-2105-13-79
PMCID: PMC3416704

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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