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Article

Expression of ABC Efflux Transporters in Placenta from Women with Insulin-Managed Diabetes

27 Apr 2012

Abstract excerpt

Drug efflux transporters in the placenta can significantly influence the materno-fetal transfer of a diverse array of drugs and other xenobiotics. To determine if clinically important drug efflux transporter expression is altered in pregnancies complicated by gestational diabetes mellitus (GDM-I) or type 1 diabetes mellitus (T1DM-I), we compared the expression of multidrug resistance protein 1 (MDR1), multidrug...

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PMID: 22558111
DOI: 10.1371/journal.pone.0035027

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