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Article

ABC drug transporter expression and functional activity in trophoblast-like cell lines and differentiating primary trophoblast

2 Dec 2005

Abstract excerpt

ATP-binding cassette (ABC) efflux transporters are expressed in the human placenta where they are thought to help protect the fetus from xenobiotics. To evaluate models for analysis of ABC transporter function and regulation in the placenta, we have characterized the expression and activity of multidrug resistance (MDR) 1/P glycoprotein (Pgp), MDR3/Pgp, breast cancer resistance protein (BCRP), and multidrug...

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Identifiers

PMID: 16322349
DOI: 10.1152/ajpregu.00630.2005

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Source receipt: pubmed, retrieved 7 Sept 2026.

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