Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Expression of breast cancer resistance protein (BCRP/ABCG2) in human placenta throughout gestation and at term before and after labor

1 Dec 2006

Abstract excerpt

Breast cancer resistance protein, BCRP, is a multidrug resistance protein that is highly expressed in the human placenta. In cancer tissues, this protein actively extrudes a wide variety of chemically and structurally unrelated chemotherapeutic drugs and other compounds. Studies in mice have shown that in the absence of BCRP activity in the placenta, there is a 2-fold increase in the uptake in BCRP substrates...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Drug Transport and Resistance Mechanisms
Share to Pharmacological Effects and Toxicity Studies
Share to Pregnancy and Medication Impact

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 17487233
DOI: 10.1139/y06-078

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Expression of breast cancer resistance protein (BCRP/ABCG2) in human placenta throughout gestation and at term before and after laborPMID 17487233Read ↗

BCRP/ABCG2 in the Placenta: Expression, Function and RegulationSemantic proximity Read ↗

An update on expression and function of P-gp/ABCB1 and BCRP/ABCG2 in the placenta and fetusSemantic proximity Read ↗

Fetoprotective activity of breast cancer resistance protein (BCRP, ABCG2): expression and function throughout pregnancySemantic proximity Read ↗

Placental P-glycoprotein and breast cancer resistance protein: influence of polymorphisms on fetal drug exposure and physiology.Semantic proximity Read ↗

ATP-Binding Cassette Efflux Transporters in Human PlacentaSemantic proximity Read ↗

Regional expression of the BCRP/ABCG2 transporter in term human placentasSemantic proximity Read ↗

ABC drug transporter expression and functional activity in trophoblast-like cell lines and differentiating primary trophoblastSemantic proximity Read ↗

Interindividual Regulation of the Breast Cancer Resistance Protein/ABCG2 Transporter in Term Human Placentas.Semantic proximity Read ↗

Breast Cancer Resistance Protein (BCRP/ABCG2) Inhibits Extra Villous Trophoblast Migration: The Impact of Bacterial and Viral InfectionSemantic proximity Read ↗

ABCB1 and ABCG2 expression in the placenta and fetus: an interspecies comparisonSemantic proximity Read ↗

Expression of the Multidrug Resistance P-Glycoprotein, (ABCB1 glycoprotein) in the Human Placenta Decreases with Advancing GestationSemantic proximity Read ↗

Gestational age‐dependent gene expression profiling of ATP ‐binding cassette transporters in the healthy human placentaSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.