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Article

SEQCHIP: a powerful method to integrate sequence and genotype data for the detection of rare variant associations.

Bioinformatics (Oxford, England) - 1 Jul 2012

Liu Dajiang J, Leal Suzanne M

Abstract excerpt

MOTIVATION: Next-generation sequencing greatly increases the capacity to detect rare-variant complex-trait associations. However, it is still expensive to sequence a large number of samples and therefore often small datasets are used. Given cost constraints, a potentially more powerful two-step strategy is to sequence a subset of the sample to discover variants, and genotype the identified variants in the...

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Identifiers

PMID: 22556370
DOI: 10.1093/bioinformatics/bts263
PMCID: PMC3381973

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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