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Comprehensive Characterization of the Coding and Non-Coding Single Nucleotide Polymorphisms in the Tumor Protein p63 (TP63) Gene Using In Silico Tools.

Biomolecules - 20 Nov 2021

Akter Shamima, Hossain Shafaat, Ali Md Ackas, Hosen Md Ismail, Shekhar Hossain Uddin

Abstract excerpt

Single nucleotide polymorphisms (SNPs) help to understand the phenotypic variations in humans. Genome-wide association studies (GWAS) have identified SNPs located in the tumor protein 63 (TP63) locus to be associated with the genetic susceptibility of cancers. However, there is a lack of in-depth characterization of the structural and functional impacts of the SNPs located at the TP63 gene. The current study was...

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PMID: 34827731
DOI: 10.3390/biom11111733
PMCID: PMC8637305

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