Article
Conserved distal promoter of the agouti signaling protein (ASIP) gene controls sexual dichromatism in chickens.
General and comparative endocrinology - 1 Jun 2012
Oribe Eri, Fukao Ayaka, Yoshihara Chihiro, Mendori Misa, Rosal Karen G, Takahashi Sumio, Takeuchi Sakae
Abstract excerpt
Brilliant plumage is typical of male birds, thus sexual plumage dichromatism is seen in many avian species; however, the molecular mechanism underlying this remains unclear. The agouti signaling protein (ASIP) is a paracrine factor that stimulates yellow/red pigment (pheomelanin) synthesis and inhibits black/brown pigment (eumelanin) synthesis in follicular melanocytes. In mammals, the distal promoter of the ASIP...
Topics
- Agouti Signaling Protein
- Animals
- Chickens
- Conserved Sequence
- Estrogens
- Female
- Gene Expression Regulation, Developmental
- Male
- Models, Biological
- Phenotype
- Pigmentation
- Promoter Regions, Genetic
- Sex Differentiation
- Sexual Maturation