Article
Characterization of Japanese quail yellow as a genomic deletion upstream of the avian homolog of the mammalian ASIP (agouti) gene.
Genetics - 1 Feb 2008
Nadeau Nicola J, Minvielle Francis, Ito Shin'ichi, Inoue-Murayama Miho, Gourichon David, Follett Sarah A, Burke Terry, Mundy Nicholas I
Abstract excerpt
ASIP is an important pigmentation gene responsible for dorsoventral and hair-cycle-specific melanin-based color patterning in mammals. We report some of the first evidence that the avian ASIP gene has a role in pigmentation. We have characterized the genetic basis of the homozygous lethal Japanese quail yellow mutation as a >90-kb deletion upstream of ASIP. This deletion encompasses almost the entire coding...
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