An enhancer of Agouti contributes to parallel evolution of cryptically colored beach mice.

doi:10.1073/pnas.2202862119

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Article

An enhancer of Agouti contributes to parallel evolution of cryptically colored beach mice.

Proceedings of the National Academy of Sciences of the United States of America - 5 Jul 2022

Wooldridge T Brock, Kautt Andreas F, Lassance Jean-Marc, McFadden Sade, Domingues Vera S, Mallarino Ricardo, Hoekstra Hopi E

Abstract excerpt

Identifying the genetic basis of repeatedly evolved traits provides a way to reconstruct their evolutionary history and ultimately investigate the predictability of evolution. Here, we focus on the oldfield mouse (Peromyscus polionotus), which occurs in the southeastern United States, where it exhibits considerable color variation. Dorsal coats range from dark brown in mainland mice to near white in mice...

Topics

Agouti Signaling Protein
Alleles
Animals
Biological Evolution
Enhancer Elements, Genetic
Genes, Reporter
Peromyscus
Skin Pigmentation

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Identifiers

PMID: 35776547
DOI: 10.1073/pnas.2202862119
PMCID: PMC9271204

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