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Article

The O-glycan pathway is associated with in vitro sensitivity to gemcitabine and overall survival from ovarian cancer

26 Apr 2012

Abstract excerpt

Ovarian cancer (OVCA) is the most lethal gynecological malignancy. The high mortality rate associated with this disease is due in large part to the development of resistance to chemotherapy; however, the biological basis of this remains unclear. Gemcitabine is frequently used for the treatment of patients with platinum-resistant OVCA. We report molecular signaling pathways associated with OVCA response to...

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PMID: 22552627
DOI: 10.3892/ijo.2012.1451

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