Back to search

Article

Combination of gene set signatures correlates with response to nivolumab in platinum-resistant ovarian cancer

2021-04-07

Abstract excerpt

<h4>Background: </h4> Based on our previous phase II clinical trial of anti-programmed death-1 (PD-1) antibody nivolumab for platinum-resistant ovarian cancer (n=19, UMIN000005714), we aimed to identify the therapeutic response biomarkers to nivolumab in ovarian cancer. Methods Tumor gene expressions were evaluated by proliferative, mesenchymal, differentiated, and immunoreactive gene signatures derived from high-...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work
a89fa0cd-8c84-595b-ae93-e8232675c915
DOI
10.21203/rs.3.rs-371906/v1
Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest
Interactive article relationship graphSelect a related publication card to move it into the centre and load its closest explainable connections. Solid lines are source-backed structured connections. Dashed lines are semantic discovery signals and are not scientific evidence.
Combination of gene set signatures correlates with response to nivolumab in platinum-resistant ovarian cancerDOI 10.21203/rs.3.rs-371906/v1
Neoadjuvant Chemotherapy Modulates the Tumor Microenvironment in High-Grade Serous Ovarian CancerSemantic proximity
Molecular Characterization of Non-responders to Chemotherapy in Serous Ovarian Cancer.Semantic proximity
Integrated Analysis of Gene Expression Profiles Associated with Response of Platinum/Paclitaxel-Based Treatment in Epithelial Ovarian CancerSemantic proximity
Gene networks and expression quantitative trait loci associated with platinum-based chemotherapy response in high-grade serous ovarian cancerSemantic proximity
Gene networks and expression quantitative trait loci associated with platinum-based chemotherapy response in high-grade serous ovarian cancerSemantic proximity
Top differentially expressed genes between patients with progressive disease and those with complete remission following the first course of treatment in different cancer typesSemantic proximity
Large-scale integrated analysis of ovarian cancer tumors and cell lines identifies an individualized gene expression signature for predicting response to platinum-based chemotherapySemantic proximity
Integration of histopathological images and multi-dimensional omics analyses predicts molecular features and prognosis in high-grade serous ovarian cancer.Semantic proximity
Top differentially expressed genes between patients with progressive disease and those with complete remission following the first course of treatment in different cancer typesSemantic proximity
A three-gene expression score for predicting clinical benefit to anti-PD-1 blockade in advanced renal cell carcinomaSemantic proximity
Prediction of response to promising first-line chemotherapy in ovarian cancer patients with residual peritoneal tumors: Practical biomarkers and robust multiplex modelsSemantic proximity
Predicting prognosis and drug sensitivity of ovarian cancer patients using different Programmed cell death patternsSemantic proximity
Select a neighboring publication to make it the new centre.