Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Decreased microRNA‐142‐3p/5p expression causes CD4+ T cell activation and B cell hyperstimulation in systemic lupus erythematosus

2 May 2012

Abstract excerpt

OBJECTIVE: To examine the role of microRNA-142-3p/5p (miR-142-3p/5p) in the development of autoimmunity in patients with systemic lupus erythematosus (SLE). METHODS: MicroRNA-142-3p/5p expression levels were determined by real-time quantitative polymerase chain reaction, and potential target genes were verified using luciferase reporter gene assays. The effects of miR-142-3p/5p on T cell function were assessed by...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Liver Diseases and Immunity
Share to MicroRNA in disease regulation
Share to Systemic Lupus Erythematosus Research

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 22549634
DOI: 10.1002/art.34505

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Decreased microRNA‐142‐3p/5p expression causes CD4+ T cell activation and B cell hyperstimulation in systemic lupus erythematosusPMID 22549634Read ↗

Inhibition of miR-22-3p reduces kidney disease associated with systemic lupus erythematosusSemantic proximity Read ↗

Decreased microRNA(miR)-145 and increased miR-224 expression in T cells from patients with systemic lupus erythematosus involved in lupus immunopathogenesisSemantic proximity Read ↗

Circulating MicroRNA Expression Profiles Associated With Systemic Lupus ErythematosusSemantic proximity Read ↗

Immunological Involvement of MicroRNAs in the Key Events of Systemic Lupus ErythematosusSemantic proximity Read ↗

Regulation of B-cell function by miRNAs impacting Systemic lupus erythematosus progressionSemantic proximity Read ↗

MicroRNA Regulation in Systemic Lupus Erythematosus PathogenesisSemantic proximity Read ↗

MicroRNAs in the pathogenesis of systemic lupus erythematosus.Semantic proximity Read ↗

MicroRNA expression profiles identify disease-specific alterations in systemic lupus erythematosus and primary Sjögren's syndromeSemantic proximity Read ↗

Identification of novel microRNA signatures linked to human lupus disease activity and pathogenesis: miR-21 regulates aberrant T cell responses through regulation of PDCD4 expression.Semantic proximity Read ↗

Inflammatory factor-mediated miR-155/SOCS1 signaling axis leads to Treg impairment in systemic lupus erythematosusSemantic proximity Read ↗

Microarray analysis of microRNA expression in peripheral blood cells of systemic lupus erythematosus patientsSemantic proximity Read ↗

A functional variant in microRNA-146a promoter modulates its expression and confers disease risk for systemic lupus erythematosus.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.