Article
Identification of novel microRNA signatures linked to human lupus disease activity and pathogenesis: miR-21 regulates aberrant T cell responses through regulation of PDCD4 expression.
Annals of the rheumatic diseases - 1 Aug 2011
Stagakis Elias, Bertsias George, Verginis Panayotis, Nakou Magdalene, Hatziapostolou Maria, Kritikos Heraklis, Iliopoulos Dimitrios, Boumpas Dimitrios T
Abstract excerpt
OBJECTIVE: MicroRNAs (miRNAs) regulate the expression of genes involved in immune activation. A study was undertaken to characterise the miRNA signature and identify novel genes involved in the regulation of immune responses in systemic lupus erythematosus (SLE). METHODS: The expression of 365 mi...
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