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Article

Genetic polymorphism of XRCC1 correlated with response to oxaliplatin-based chemotherapy in advanced colorectal cancer.

Pathology oncology research : POR - 1 Oct 2012

Lv Hongying, Li Qicai, Qiu Wengsheng, Xiang Jinyu, Wei Hongjun, Liang Hua, Sui Aihua, Liang Jun

Abstract excerpt

To examine the association between genetic polymorphisms of XRCC1 Arg399Gln(G→A) and response to oxaliplatin-based chemotherapy in advanced colorectal cancer. XRCC1 genotypes of totally 99 patients(37 stage III, 62 stage IV)with advanced colorectal cancer treated with oxaliplatin-based chemotherapy were detected by TaqMan-MGB probe allelic discrimination method. And clinical response of 62 patients in stage...

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PMID: 22549274
DOI: 10.1007/s12253-012-9536-6

Genes

XRCC1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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