Prediction of genetic polymorphisms of DNA repair genes XRCC1 and XRCC3 in the survival of colorectal cancer receiving chemotherapy in the Chinese population.

Abstract excerpt

BACKGROUND/AIMS: We aimed to detect the distribution of DNA repair genes XRCC1 and XRCC3 genotypes in the survival of colorectal cancer patients receiving chemotherapy in the Chinese population. METHODOLOGY: The prospective study was conducted with 432 cases treated with 5-FU and oxaliplatin as first-line chemotherapy. All the patients were followed-up from May 2006 to May 2011 and 168 patients died during...

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