Spatiotemporal network motif reveals the biological traits of developmental gene regulatory networks in Drosophila melanogaster.

Abstract excerpt

BACKGROUND: Network motifs provided a "conceptual tool" for understanding the functional principles of biological networks, but such motifs have primarily been used to consider static network structures. Static networks, however, cannot be used to reveal time- and region-specific traits of biological systems. To overcome this limitation, we proposed the concept of a "spatiotemporal network motif," a...

Topics

• Animals
• Computational Biology
• Drosophila melanogaster
• Gene Regulatory Networks
• Genes, Insect
• Models, Genetic
• Phenotype
• Spatio-Temporal Analysis