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Topological analysis of protein co-abundance networks identifies novel host targets important for HCV infection and pathogenesis

30 Apr 2012

Abstract excerpt

BACKGROUND: High-throughput methods for obtaining global measurements of transcript and protein levels in biological samples has provided a large amount of data for identification of 'target' genes and proteins of interest. These targets may be mediators of functional processes involved in disease and therefore represent key points of control for viruses and bacterial pathogens. Genes and proteins that are the...

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PMID: 22546282
DOI: 10.1186/1752-0509-6-28

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