Article
Capulet and Slingshot share overlapping functions during Drosophila eye morphogenesis.
Journal of biomedical science - 30 Apr 2012
Lin Chiao-Ming, Lin Pei-Yi, Li Yu-Chiao, Hsu Jui-Chou
Abstract excerpt
BACKGROUND: CAP/Capulet (Capt), Slingshot (Ssh) and Cofilin/Twinstar (Tsr) are actin-binding proteins that restrict actin polymerization. Previously, it was shown that low resolution analyses of loss-of-function mutations in capt, ssh and tsr all show ectopic F-actin accumulation in various Drosophila tissues. In contrast, RNAi depletion of capt, tsr and ssh in Drosophila S2 cells all affect actin-based lamella...
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