Article
Using latent class growth analysis to identify childhood wheeze phenotypes in an urban birth cohort.
Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology - 1 May 2012
Chen Qixuan, Just Allan C, Miller Rachel L, Perzanowski Matthew S, Goldstein Inge F, Perera Frederica P, Whyatt Robin M
Abstract excerpt
BACKGROUND: To advance asthma cohort research, we need a method that can use longitudinal data, including when collected at irregular intervals, to model multiple phenotypes of wheeze and identify both time-invariant (eg, sex) and time-varying (eg, environmental exposure) risk factors. OBJECTIVE: To demonstrate the use of latent class growth analysis (LCGA) in defining phenotypes of wheeze and examining the...
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