Article
Clinical and epidemiologic phenotypes of childhood asthma.
American journal of respiratory and critical care medicine - 15 Jan 2014
Depner Martin, Fuchs Oliver, Genuneit Jon, Karvonen Anne M, Hyvärinen Anne, Kaulek Vincent, Roduit Caroline, Weber Juliane, Schaub Bianca, Lauener Roger, Kabesch Michael, Pfefferle Petra Ina, Frey Urs, Pekkanen Juha, Dalphin Jean-Charles, Riedler Josef, Braun-Fahrländer Charlotte, von Mutius Erika, Ege Markus J
Abstract excerpt
RATIONALE: Clinical and epidemiologic approaches have identified two distinct sets of classifications for asthma and wheeze phenotypes. OBJECTIVES: To compare epidemiologic phenotype definitions identified by latent class analysis (LCA) with clinical phenotypes based on patient histories, diagnostic work-up, and treatment responses. To relate phenotypes to genetic and environmental determinants as well as...
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