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TaqIA polymorphism in dopamine D2 receptor gene complicates weight maintenance in younger obese patients.

Nutrition (Burbank, Los Angeles County, Calif.) - 1 Oct 2012

Winkler Julia K, Woehning Annika, Schultz Jobst-Hendrik, Brune Maik, Beaton Nigel, Challa Tenagne Delessa, Minkova Stella, Roeder Eva, Nawroth Peter P, Friederich Hans-Christoph, Wolfrum Christian, Rudofsky Gottfried

Abstract excerpt

OBJECTIVE: The A1 allele of the TaqIA polymorphism in the dopamine D2 receptor gene (rs1800497) has been associated with obesity. However, the effect of the polymorphism on the success in weight loss and/or weight maintenance during weight-loss programs has not been evaluated thus far. METHODS: The rs1800497 was genotyped in 202 (135 female, 67 male) severely obese individuals with an initial body mass index of...

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Identifiers

PMID: 22541053
DOI: 10.1016/j.nut.2011.12.018

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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