Article
The A-allele of the common FTO gene variant rs9939609 complicates weight maintenance in severe obese patients.
International journal of obesity (2005) - 1 Jan 2013
Woehning A, Schultz J-H, Roeder E, Moeltner A, Isermann B, Nawroth P P, Wolfrum C, Rudofsky G
Abstract excerpt
OBJECTIVE: The A-allele of the fat mass and obesity-associated (FTO) gene variant rs9939609 has been associated with increased body weight, whereas no effect on weight loss during weight reduction programs has been observed. We questioned whether the AA-genotype interferes with weight stabilization after weight loss. DESIGN: We conducted a monocentric, longitudinal study involving obese individuals. The FTO gene...
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