Article
Genetic epidemiology of complex phenotypes.
Annals of human genetics - 1 Oct 1991
Morton N E, Shields D C, Collins A
Abstract excerpt
A theory is given for complex phenotypes represented by an ordered polychotomy separately for affected (as severity) and for normals (as diathesis), with consideration of history, ascertainment, sampling frames, and phenotype systems. Nonrandom selection of probands by severity is permitted. Both probit and logistic models are developed in a form compatible with segregation and/or linkage analysis. Probabilities...
Topics
- Genetics, Population
- Models, Genetic
- Phenotype