Article
Association between arachidonate 5-lipoxygenase-activating protein (ALOX5AP) and lung function in a Korean population.
Scandinavian journal of immunology - 1 Aug 2012
Ro M, Kim S, Pyun J-A, Shin C, Cho N H, Lee J-Y, Koh I, Kwack K
Abstract excerpt
Arachidonate 5-lipoxygenase-activating protein (ALOX5AP) plays a role in the 5-lipoxygenase (LO) pathway, which includes the LTC(4), LTD(4), LTE(4) and LTB(4). These leukotrienes are known causative factors of asthma, allergy, atopy and cardiovascular diseases. ALOX5AP lacks enzyme activity and acts by helping 5-LO function. In this study, healthy and general subjects who live in rural and urban areas of Korea...
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