Article
Genotyping from saliva with a one-step microdevice.
Lab on a chip - 21 Jul 2012
Pjescic Ilija, Crews Niel
Abstract excerpt
This paper presents a disposable microfluidic device for on-chip lysing, PCR, and analysis in one continuous-flow process. Male-female sex determination was performed with human saliva in less than 20 min from spit to finish, and requiring only seconds of manual sample handling. This genetic analysis was based on the amplification and detection of the DYZ1 repeat region unique to the Y-chromosome. The...
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