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Article

Multiplex STR amplification sensitivity in a silicon microchip.

Scientific reports - 29 Jun 2018

Cornelis Senne, Fauvart Maarten, Gansemans Yannick, Vander Plaetsen Ann-Sophie, Colle Frederik, Wiederkehr Rodrigo S, Deforce Dieter, Stakenborg Tim, Van Nieuwerburgh Filip

Abstract excerpt

The demand for solutions to perform forensic DNA profiling outside of centralized laboratories is increasing. We here demonstrate highly sensitive STR amplification using a silicon micro-PCR (µPCR) chip. Exploiting industry-standard semiconductor manufacturing processes, a device was fabricated that features a small form factor thanks to an integrated heating element covering three parallel micro-reactors with a...

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Identifiers

PMID: 29959383
DOI: 10.1038/s41598-018-28229-9
PMCID: PMC6026139

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

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