Article
Ectopic overexpression of swine PPARγ2 upregulated adipocyte genes expression and triacylglycerol in skeletal muscle of mice.
Transgenic research - 1 Dec 2012
Huang Jinliang, Xiong Yuanzhu, Li Ting, Zhang Lin, Zhang Zijian, Zuo Bo, Xu Dequan, Ren Zhuqing
Abstract excerpt
Peroxisome proliferator-activated receptor γ2 (PPARγ2) is a key regulator of adipocyte differentiation, fatty acid uptake and storage in mammals. The primary goal of the present study was to investigate the consequences of PPARγ2 overexpression in the muscle. A swine muscle creatine kinase promoter was used to drive swine PPARγ2 (sPPARγ2) overexpression in the muscle of a transgenic mice model. The results showed...
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