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Article

Micronucleated lymphocytes in parents of Down syndrome children.

Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas - 1 Jul 2012

Silva-Grecco R L, Navarro G C, Cruz R M, Balarin M A S

Abstract excerpt

Down syndrome (DS) is the most common disease due to an autosomal aneuploidy in live born children and also the major known genetic cause of mental retardation. The risk of a DS pregnancy increases substantially with increasing maternal age. However, several women aged less than 35 years at conception have a child with DS. The micronucleus (MN) assay can identify chromosome breakage or chromosome malsegregation...

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Identifiers

PMID: 22527126
DOI: 10.1590/s0100-879x2012007500063
PMCID: PMC3854276

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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