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Article

Immediate vs. delayed treatment in patients with acute hepatitis C based on IL28B polymorphism: a model-based analysis.

Journal of hepatology - 1 Aug 2012

Deuffic-Burban Sylvie, Castel Hélène, Wiegand Johannes, Manns Michael P, Wedemeyer Heiner, Mathurin Philippe, Yazdanpanah Yazdan

Abstract excerpt

BACKGROUND & AIMS: Timing of treatment initiation in acute hepatitis C (AHC) patients is unclear. Spontaneous viral clearance argues for a "watch-and-wait" strategy. However, early initiation of treatment could increase the sustained virological response (SVR) rate. We compared three different HCV treatment initiation strategies in patients with AHC according to presence of clinical symptoms and IL28B...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 22521356
DOI: 10.1016/j.jhep.2012.03.020

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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