Article
Histone H1 affects gene imprinting and DNA methylation in Arabidopsis.
The Plant journal : for cell and molecular biology - 1 Sept 2012
Rea Matthew, Zheng Wenguang, Chen Ming, Braud Christopher, Bhangu Drutdaman, Rognan Tara N, Xiao Wenyan
Abstract excerpt
Imprinting, i.e. parent-of-origin expression of alleles, plays an important role in regulating development in mammals and plants. DNA methylation catalyzed by DNA methyltransferases plays a pivotal role in regulating imprinting by silencing parental alleles. DEMETER (DME), a DNA glycosylase functioning in the base-excision DNA repair pathway, can excise 5-methylcytosine from DNA and regulate genomic imprinting in...
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