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Article

DEMETER, a DNA glycosylase domain protein, is required for endosperm gene imprinting and seed viability in arabidopsis.

Cell - 12 Jul 2002

Choi Yeonhee, Gehring Mary, Johnson Lianna, Hannon Mike, Harada John J, Goldberg Robert B, Jacobsen Steven E, Fischer Robert L

Abstract excerpt

We isolated mutations in Arabidopsis to understand how the female gametophyte controls embryo and endosperm development. For the DEMETER (DME) gene, seed viability depends only on the maternal allele. DME encodes a large protein with DNA glycosylase and nuclear localization domains. DME is expres...

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PMID: 12150995
DOI: 10.1016/s0092-8674(02)00807-3

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-12150995-2026-09-02.1. Manifest publication-graph-cohort-2026-09-02.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

Related research

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Research trail→

Click a neighbor to travelStep 1 · 12 closest

DEMETER, a DNA glycosylase domain protein, is required for endosperm gene imprinting and seed viability in arabidopsis.PMID 12150995Read ↗

DEMETER DNA glycosylase establishes MEDEA polycomb gene self-imprinting by allele-specific demethylation.Semantic proximity Read ↗

Imprinting of the MEA Polycomb gene is controlled by antagonism between MET1 methyltransferase and DME glycosylase.Semantic proximity Read ↗

Control of DEMETER DNA demethylase gene transcription in male and female gamete companion cells in Arabidopsis thaliana.Semantic proximity Read ↗

Function of the DEMETER DNA glycosylase in the Arabidopsis thaliana male gametophyte.Semantic proximity Read ↗

Maintenance of genomic imprinting at the Arabidopsis medea locus requires zygotic DDM1 activity.Semantic proximity Read ↗

Histone H1 affects gene imprinting and DNA methylation in Arabidopsis.Semantic proximity Read ↗

DNA LIGASE I exerts a maternal effect on seed development in Arabidopsis thaliana.Semantic proximity Read ↗

Epigenetic role for the conserved Fe-S cluster biogenesis protein AtDRE2 in Arabidopsis thaliana.Semantic proximity Read ↗

Regulation of imprinted gene expression in Arabidopsis endosperm.Semantic proximity Read ↗

Extensive demethylation of repetitive elements during seed development underlies gene imprinting.Semantic proximity Read ↗

Two imprinted genes primed by DEMETER in the central cell and activated by WRKY10 in the endosperm.Semantic proximity Read ↗

One-way control of FWA imprinting in Arabidopsis endosperm by DNA methylation.Semantic proximity Read ↗

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