Association between dopamine beta hydroxylase rs5320 polymorphism and smoking behaviour in elderly Japanese.

doi:10.1038/jhg.2012.40

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Article

Association between dopamine beta hydroxylase rs5320 polymorphism and smoking behaviour in elderly Japanese.

Journal of human genetics - 1 Jun 2012

Ella Elakeche, Sato Naomi, Nishizawa Daisuke, Kageyama Shinji, Yamada Hidetaka, Kurabe Nobuya, Ishino Keiko, Tao Hong, Tanioka Fumihiko, Nozawa Akiko, Renyin Chen, Shinmura Kazuya, Ikeda Kazutaka, Sugimura Haruhiko

Abstract excerpt

The dopaminergic brain pathway is involved in many addictive behaviours, hence represents a good candidate in the study of smoking behaviour and nicotine addiction. Dopamine beta hydroxylase (DBH) is an enzyme that catalyses the conversion of dopamine into noradrenaline. This study, the first of its kind, was done to investigate the role of DBH rs5320 polymorphism in smoking behaviour of elderly Japanese. This...

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PMID: 22513716
DOI: 10.1038/jhg.2012.40

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

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