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Article

Genotype-phenotype correlations in a prospective cohort study of paediatric plaque psoriasis: lack of correlation between HLA-C*06 and family history of psoriasis.

Acta dermato-venereologica - 1 Nov 2014

Oostveen Annet M, Bergboer Judith G M, van de Kerkhof Peter C M, Zeeuwen Patrick L J M, de Jong Elke M G J, Schalkwijk Joost, Seyger Marieke M B

Abstract excerpt

This study aims to investigate associations between observed clinical parameters and known genetic risk factors of psoriasis in a well-defined prospective cohort of paediatric patients with plaque psoriasis (n = 151). Significant associations were found for paediatric-onset psoriasis with ERAP1 (p = 0.002), IL23R (p = 0.01), LCE3C_LCE3B-del (p = 0.00049) and HLA-C*06 (p = 3.15 × 10(-30)). Psoriasis severity was...

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Source

Identifiers

PMID: 24791935
DOI: 10.2340/00015555-1810

Genes

ERAP1
IFIH1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Genotype-phenotype correlations in a prospective cohort study of paediatric plaque psoriasis: lack of correlation between HLA-C*06 and family history of psoriasis.PMID 24791935Read ↗

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